Liver Health: The Role of Polyprenols and Carotenoids

How Polyprenols Can Support Liver Function

The liver is one of the most vital organs in the body, involved in metabolism, detoxification, and the synthesis of various compounds. However, various liver disorders (such as hepatitis, fatty liver disease, and cirrhosis) can impair its functions and affect overall health.

Polyprenols — Natural Bioregulators for the Liver

Polyprenols are plant compounds similar to dolichols, which are found in the cells of all living organisms. Research that began in Russia over 35 years ago has revealed that polyprenols have various beneficial properties, including supporting the health of liver cells. These data are confirmed by patents in Russia, Japan, the USA, and Europe.
Polyprenols are involved in the synthesis of glycoproteins, which are important for the normal functioning of cells. They support the process of glycosylation — the “maturation” of proteins necessary for regulating cell growth and maintaining the body's immune response. Following hepatic metabolism, polyprenols are converted into dolichols that participate in the dolichol phosphate cycle, which plays a crucial role in maintaining metabolic processes and cellular homeostasis.
Dolichol deficiency, which may occur with liver dysfunction, is associated with metabolic imbalance that compromises overall health. Therefore, polyprenols are used to maintain normal dolichol levels, which in turn helps sustain proper liver function and metabolic homeostasis.

The Role of Carotenoids for Liver Health

Carotenoids are natural pigments with antioxidant properties. They help protect liver cells from the effects of free radicals and oxidative stress, which is especially important in inflammatory processes in the liver. In particular, alpha- and beta-carotene serve as precursors of vitamin A, which maintains the health of the immune system and cell membranes.
Carotenoids also stimulate tissue repair processes, which proves particularly beneficial when liver dysfunction manifests through skin alterations or metabolic changes. Clinical studies demonstrate that regular carotenoid intake helps maintain cellular health and reduces inflammation intensity.

The Effect of Polyprenols and Carotenoids on the Liver

The combination of polyprenols and carotenoids in a 60:40 ratio helps maintain the following liver functions:
1. Cell Regeneration
Both components activate regenerative processes, helping preserve liver cell integrity and functionality.
2. Antioxidant Protection
Carotenoids help reduce oxidative stress impact on liver cells.
3. Metabolic Stimulation
Synergistic action enhances metabolic processes, optimizes liver's detoxification and synthesis functions
4. Immune System Restoration. Polyprenols activate cellular defense mechanisms. Particularly beneficial during infections or inflammatory conditions

Studies conducted in Saint Petersburg demonstrate that a 12-week course of polyprenols helped participants improve liver biochemical markers and increase blood antioxidant levels, which correlated with enhanced overall well-being and reduced severity of various symptoms. Upon completion of the course, participants showed decreased ALT and AST activity, normalized lipid profile, reduced symptoms of right hypochondrium heaviness, weakness and fatigue, with no side effects observed.

Conclusion

Keeping your liver healthy is essential for anyone who values their overall wellbeing. Our company specializes in the large-scale production and global supply of polyprenols derived from coniferous trees. Our advanced technology enables the extraction of high-molecular-weight polyprenols with preserved stereospecificity, all at a competitive market price.


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